Supplementary Material

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Since December 2019, the emergence of coronavirus disease 2019 (COVID-19) has had a major impact worldwide. This emerging virus does not only affect the respiratory system but also affects the nervous system. Cerebrovascular events have been reported as complications of COVID-19. In this review article, we summarized the epidemiology, stroke subtype, characteristics, laboratory findings, pathophysiology, risk factors and treatment of stroke in COVID-19 patients by reviewing case reports and cohort studies. On the other hand, sporadic adverse events such as systemic thromboembolism and stroke have been reported after COVID-19 vaccination. Herein, we reviewed the literature to elucidate the association between COVID-19 vaccines and stroke with the aim of assisting clinical decisions and giving people greater confidence in receiving vaccines.